Actin gamma 1 pseudogene 1 (ACTG1P1)

Actin gamma 1 pseudogene 1 (ACTG1P1) is a human pseudogene, meaning it is a genomic DNA sequence similar to the functional actin gamma 1 gene (ACTG1) but does not produce a functional protein product. Unlike ACTG1, which encodes a protein that is critical for cytoskeletal functions and is implicated in diseases such as Baraitser-Winter syndrome and progressive hearing loss, ACTG1P1 does not contribute to these biological activities and is not a therapeutic target. Key clarifications: - The functional actin gamma 1 (ACTG1) gene is therapeutically relevant and involved in cell structure and disease; however, ACTG1P1 is explicitly a pseudogene, which are generally non-coding and do not serve as drug targets or direct disease genes. - There is no evidence in genetic or pharmacological databases that ACTG1P1 is a drug target or has any established biological function, disease association, or clinical significance beyond being a genomic marker of its parent gene. - If your intent was to find a therapeutically actionable target, refer to the functional ACTG1 gene or its protein product gamma-actin. Summary interpretation: ACTG1P1 is not a protein, receptor, enzyme, transporter, or other drug target, nor is it associated with disease roles, mechanisms of action, or biomarker usage. Its inclusion as a therapeutic target would be incorrect.

Other names

Actin gamma 1 pseudogene 1ACTG1P1HGNC:146NCBI Gene: 73