Actin-like 6 pseudogene

The actin-like 6 pseudogene (ENSG00000258462) is a non-coding genomic region annotated as a pseudogene, meaning it shares sequence similarity with functional actin-like genes such as ACTL6A but does not encode a functional protein. Unlike ACTL6A, which is a chromatin remodeler implicated in cancer[1][2][3][5], the pseudogene lacks evidence for expression or protein product and is not considered relevant to drug targeting, disease mechanisms, or biomarker discovery. Its presence is likely a result of gene duplication or evolutionary inactivation and does not contribute to cellular function. Important distinction: - ACTL6A (Actin-like protein 6A) is an oncogenic chromatin remodeling subunit and a validated therapeutic target in multiple cancers[1][2][3][5]. - The actin-like 6 pseudogene is distinctly NOT the same as ACTL6A and has no known therapeutic, biological, or disease relevance. If structured or canonical information is required for ACTL6A (not the pseudogene), refer to data for "Actin-like protein 6A (ACTL6A)," which is a functional chromatin remodeling protein with roles in cancer and stem cell biology[1][2][3][5].

Other names

actin-like 6 pseudogene