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Actin-like 8 pseudogene

Molecular classification
Other
01

Overview

The actin-like 8 pseudogene (ENSG00000278687) is a non-functional genomic element related to the protein-coding gene ACTL8. Like other pseudogenes, it does not encode a functional protein and is generally not considered a direct therapeutic target. Pseudogenes can have regulatory roles or serve as biomarkers in cancer genomics, but there is currently no evidence that actin-like 8 pseudogene is a validated drug target or involved in canonical biological processes. ACTL8P/ENSG00000278687 is a pseudogene, which means it is a non-functional relic of a gene. It should not be confused with ACTL8 (actin-like protein 8), which is a protein-coding gene with demonstrated roles in cancer cell proliferation and may be a potential target for therapy in some contexts. Pseudogenes, including actin-like 8 pseudogene, may have regulatory functions in gene expression and could serve as biomarkers in some cancer studies, but their roles are distinct from classical therapeutic targets.

Other names
ACTL8PACTL8 pseudogene
02

Disease associations

Other
03

Biomarkers

May be explored as a marker in cancer subtyping or patient stratification, as is sometimes the case with pseudogenes

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