Activating transcription factor 4 pseudogene 3 (ATF4P3)

Activating transcription factor 4 pseudogene 3 (ATF4P3) is a pseudogene of the activating transcription factor 4 (ATF4) gene. Pseudogenes are DNA sequences resembling known genes but are typically nonfunctional due to mutations that prevent their transcription or translation. ATF4P3 is located in the human genome and also referred to as ATF4C, but it does not encode a functional protein and has no recognized biological or therapeutic function. There is no evidence that ATF4P3 serves as a therapeutic target, biomarker, or has a role in disease or pharmacology[6]. Key context: ATF4P3 is not the same as the functional ATF4 gene, which encodes a stress response transcription factor involved in various disease processes, including cancer and metabolic regulation[1][3][4][5][7]. ATF4P3 is one of the described ATF4-related pseudogenes, with no known expression as a protein or role as a therapeutic target[6]. Assessment: The entry "activating transcription factor 4 pseudogene 3" or "ATF4P3" refers only to a pseudogene, not to a druggable/receptor target or biologically active molecule[6]. Most structured fields (functions, drug interactions, etc.) are not applicable to pseudogenes unless noncoding RNA function is specifically documented; for ATF4P3, such data is lacking.

Other names

ATF4C