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Target intelligence / Profile preview
Activin receptor type-1 (ACVR1)
- Target
- ACVR1
- Molecular classification
- Receptor, Serine/threonine-protein kinase, Transmembrane protein
01
Overview
- Other names
- Activin A receptor, type IALK-2 (activin receptor-like kinase 2)ACTR-IACVRLK2
02
Biological functions
Signal transduction (BMP and activin pathways)Bone morphogenesis and skeletal developmentCell differentiation (osteoblast differentiation, endocardial cushion formation)Heart developmentBlood vessel morphogenesisRegulation of transcription by RNA polymerase IINegative regulation of G1/S transition of mitotic cell cycle
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