Activity against fungal species

Activity against fungal species" does not represent a specific therapeutic target. Rather, it refers to the ability of a drug or compound to inhibit the growth of, or kill, fungi. Many different molecular targets and mechanisms can underlie antifungal activity, including—but not limited to—fungal cell wall components (e.g., 1,3-β-glucan synthase targeted by echinocandins), fungal membrane components (e.g., ergosterol targeted by polyenes and azoles), and fungal nucleic acid synthesis pathways (e.g., flucytosine)[1][2][5][6]. Therefore, this term does not specify a unique target or molecular entity and is unsuitable as a canonical target designation in structured databases.