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The term "acute myeloid leukemia cell antigen" is not a specific therapeutic target but rather a general descriptor for a category of antigens expressed on AML cells. This represents multiple distinct molecular targets rather than a single entity. It functions as an umbrella term encompassing numerous leukemia-associated antigens (LAAs), each with distinct molecular structures and classifications, expression patterns across AML subtypes, immunogenic properties, and therapeutic applications. Examples of specific AML-associated antigens include Cyclin-A1, U5 snRNP200, CD33, Wilms tumor protein 1 (WT1), NPM1 mutant protein, Lewis Y (LeY) antigen, IL12RB1, and CD96. To obtain structured information for a therapeutic target database, specific molecular entities would need to be specified.
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