ADAM metallopeptidase domain 20 pseudogene (ADAM20P)

The ADAM metallopeptidase domain 20 pseudogene is a non-coding, non-functional genomic sequence similar to the ADAM20 gene, which encodes a testis-specific disintegrin and metalloprotease family member involved in fertilization and sperm maturation in humans. As a pseudogene, it does not encode a functional protein and has no known biological or therapeutic role. It is sometimes listed with aliases such as ADAM20P1 or C14orf55. There is a functional gene, ADAM20 (Disintegrin and metalloproteinase domain-containing protein 20), which encodes a metallopeptidase enzyme involved in sperm maturation and fertilization. However, ENSG00000274330 specifically refers to a pseudogene, not this protein-coding gene. In drug discovery and biology, pseudogenes like this are generally not considered direct therapeutic targets.

Other names

ADAM20P1C14orf55

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