ADAMTS7 pseudogene 5 (ADAMTS7P5)

ADAMTS7 pseudogene 5 (ADAMTS7P5) is a pseudogene—an inactive genomic sequence derived from the functional *ADAMTS7* gene. It does not encode an active protein and is not implicated in biological processes or disease mechanisms. Its existence can pose a technical challenge to genetic studies on *ADAMTS7* due to high sequence similarity, which may interfere with variant discovery in short-read sequencing data[3]. In contrast, the functional *ADAMTS7* gene encodes an extracellular metalloproteinase that regulates vascular smooth muscle cell migration, cartilage degradation, and is implicated in coronary artery disease and arthritis[1][3][4][5]. ADAMTS7P5 should not be considered a drug target, receptor, biomarker, or disease-causing gene.

Other names

ADAMTS7P5ADAMTS7 pseudogene 5

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