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Adenosine triphosphate-dependent enzymes are a class of enzymes that require adenosine triphosphate (ATP) to function. ATP serves as the primary energy currency in cells, providing the necessary energy for various biochemical reactions. These enzymes harness the chemical energy stored in ATP by hydrolyzing it to adenosine diphosphate (ADP) or adenosine monophosphate (AMP), releasing free phosphate and usable energy. They regulate processes like neurotransmission, immune responses, muscle activity, biosynthesis pathways, active transport mechanisms, cell signaling cascades, and more. Dysfunction or mutations affecting these enzymes can lead to metabolic disorders or diseases.
Inhibition of ATP hydrolysis, modulation of phosphorylation
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