Target intelligence / Profile preview

Adenosma glutinosum extract

Molecular classification
Plant extract, Complex mixture, Herbal medicine
01

Overview

Adenosma glutinosum extract is a complex botanical preparation derived from the aerial parts of the Adenosma glutinosum plant, which is native to Southeast Asia and frequently used in traditional Vietnamese medicine (Nhân trần). It is not a specific molecular target (such as a receptor or enzyme) but is instead a therapeutic substance containing a variety of bioactive compounds, including essential oils (like cineole and fenchone), flavonoids, and saponins. The extract is primarily valued for its hepatoprotective and choleretic properties, making it a common treatment for liver ailments, hepatitis, and jaundice by promoting bile production and protecting liver tissue from toxins. Additionally, it demonstrates significant anti-inflammatory and antimicrobial activities, contributing to its use in treating infections and digestive issues. Because it consists of numerous chemical constituents that affect multiple biological pathways simultaneously, it is categorized as a complex herbal mixture rather than a singular drug target.

Other names
Nhân trầnAdenosma glutinosum (L.) DruceMao xạ hươngNhan tran extract
02

Mechanism of action

The extract functions as a multi-component therapeutic agent that stimulates bile secretion and flow (choleretic effect), protects hepatocytes from oxidative stress via free radical scavenging, and modulates inflammatory pathways to reduce liver damage.

03

Biological functions

HepatoprotectiveCholeretic activityAnti-inflammatoryAntimicrobial activityAntioxidant
04

Disease associations

HepatitisJaundiceDigestive disordersInfectionInflammation
05

Safety considerations

Potential herb-drug interactions via modulation of Cytochrome P450 enzymesVariability in bioactive compound concentration due to lack of standardizationLimited clinical safety data regarding long-term high-dose consumption
06

Biomarkers

Alanine aminotransferase (ALT)Aspartate aminotransferase (AST)Bilirubin

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