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Target intelligence / Profile preview
Adenovirus-Infected Cell (AdV-Infected Cell)
- Target
- AdV-Infected Cell
- Molecular classification
- Cell, Infected Cell
01
Overview
An adenovirus-infected cell is a host cell that has been invaded by an adenovirus. Once inside, the virus hijacks cellular machinery to replicate its genome and produce new viral particles. These infections can cause a range of illnesses and the infected cells display viral antigens on their surface, triggering immune responses. Adenoviruses are also used as vectors for vaccines and gene therapy.
- Other names
- Adenovirus infected host cellCell infected with AdenovirusAdV-infected host cell
02
Mechanism of action
N/A
03
Biological functions
Viral replicationHost cell response to viral infectionViral pathogenesisAntigen presentationCell lysis
04
Disease associations
Respiratory illnessConjunctivitisGastroenteritisInfectionImmunodeficiency-related complications
05
Safety considerations
Potential for severe infection in immunocompromised individualsRisk of insertional mutagenesis (gene therapy)Immune response to viral vector (gene therapy/vaccines)
06
Interacting drugs
Antiviral drugs (experimental)
2 more in the full profile.
07
Biomarkers
Viral loadAdenovirus-specific antibodiesT cell response to adenovirus antigens
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