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Adenylate cyclase type 2 (None)

Target: None
Molecular classification: Enzyme, Adenylyl cyclase

Overview

Adenylate cyclase type 2 (ADCY2) is a membrane-associated enzyme that catalyzes the conversion of ATP to cyclic AMP (cAMP), a crucial secondary messenger in various signaling pathways. It is primarily expressed in the brain and plays a role in neurotransmission, hormone action, and cellular responses to external stimuli. ADCY2 is regulated by G-protein signaling and requires magnesium ions for its activity. Altered regulation of ADCY2 has been associated with neurological functions.

Mechanism of action

Directly catalyzes the conversion of ATP to cAMP, increasing intracellular cAMP levels.

Biological functions

Signal transductioncAMP biosynthetic process

Disease associations

Neurological disorders

Interacting drugs

Forskolin

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