Adenylate kinase 2 pseudogene

Adenylate kinase 2 pseudogene is an intronless processed pseudogene of the adenylate kinase 2 gene sequence. While the functional AK2 gene encodes a mitochondrial enzyme involved in nucleotide homeostasis[1][4][7], the pseudogene copy is not normally transcribed or translated into functional protein and lacks demonstrated biological activity or disease association[2][5][6]. Pseudogenes such as this are generally considered non-functional relics of gene duplication or retrotransposition events, and are not therapeutic targets. Key clarifications: - The gene designated here (adenylate kinase 2 pseudogene / ENSG00000185839 / AK2B / AK2P1) is not the functional adenylate kinase 2 gene (AK2, ENSG00000004455), which is an enzyme essential for cellular energy metabolism[1][4][7]. - This pseudogene neither encodes a protein nor serves as a recognized drug target. - There are other related pseudogenes colloquially termed AK2P1, AK2P2, etc., but none are therapeutically relevant.

Other names

AK2BAK2P1adenylate kinase 2 pseudogene 1adenylate kinase 2B pseudogene