Adenylate kinase 6 pseudogene 2 (AK6P2)

Adenylate kinase 6 pseudogene 2 (AK6P2) is a genomic DNA sequence resembling the adenylate kinase 6 (AK6) gene but does not encode a functional protein. It is annotated as a pseudogene in genomic databases, indicating it is a non-coding gene copy that likely arose from duplication or retrotransposition and accumulated disabling mutations. Unlike its parent gene AK6, which encodes a nuclear-localized enzyme involved in nucleotide metabolism and cell energetics, AK6P2 has no evidence supporting its role as a therapeutic target, enzyme, transporter, receptor, or disease biomarker. Additional details: - Canonical target confusion: Although AK6 is biologically active and linked to several crucial cell processes, AK6P2 does not code for a functional protein and so is not a valid therapeutic target. - Nomenclature: The presence of “pseudogene” in the name indicates that AK6P2 should not be confused with AK6 (adenylate kinase 6), which is the actual protein-coding gene and potential target. - Aliases: There are no notable alternative names beyond "AK6P2".

Other names

AK6P2