Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Adenylate kinase 7 (AK7)
- Target
- AK7
- Molecular classification
- Enzyme, Nucleoside monophosphate kinase, Phosphotransferase
01
Overview
Adenylate kinase 7 (AK7) is a protein-coding enzyme that belongs to the adenylate kinase family and is involved in cellular energy homeostasis through catalysis of the reversible transfer of a phosphate group between nucleoside triphosphates and monophosphates. It has highest activity towards adenosine monophosphate (AMP) and weaker activity towards other nucleoside monophosphates. AK7 plays a crucial role in the maintenance of ciliary structure and function, and mutations in this gene are associated with diseases such as primary ciliary dyskinesia and certain forms of male infertility[2][5][1][4].
- Other names
- AK7AK 7FLJ32864FAP75CFAP75ATP-AMP transphosphorylase 7SPGF27putative adenylate kinase 7
02
Biological functions
Energy homeostasisCatalysis of reversible phosphorylation of adenine nucleotidesMaintenance of ciliary structure and function[1][2][5]
03
Disease associations
Primary ciliary dyskinesia (PCD)[2][4]Spermatogenic failure 27[2]Non-syndromic male infertility due to sperm motility disorder[2]
04
Biomarkers
AK7 mutations/deficiency (biomarker for primary ciliary dyskinesia and related motility disorders)[2][4]
Beyond the preview
Go deeper on Adenylate kinase 7 (AK7).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Adenylate kinase 7 (AK7).