Target intelligence / Profile preview

Adipocyte Membrane

Molecular classification
Cell membrane, Lipid bilayer, Protein complex
01

Overview

The adipocyte membrane is the plasma membrane of adipocytes, specialized cells for storing energy as fat. It plays a crucial role in maintaining cell integrity, mediating metabolic exchanges, and facilitating signaling processes essential for energy homeostasis and endocrine functions. It regulates the transport of nutrients and hormones, hosts receptors for signaling pathways like insulin and catecholamines, and facilitates the secretion of adipokines like leptin and adiponectin. Its dysfunction is implicated in obesity and related metabolic disorders.

Other names
Adipocyte plasma membraneFat cell membraneLipocyte membrane
02

Mechanism of action

Varies depending on the interacting molecule; examples include activation of insulin receptor signaling, modulation of glucose transport, alteration of lipolysis/lipogenesis.

03

Biological functions

Barrier functionNutrient transportHormone signalingAdipokine secretionMetabolic regulationEnergy homeostasis
04

Disease associations

ObesityInsulin resistanceType 2 diabetes mellitusMetabolic syndrome
05

Safety considerations

Altered membrane function in obesityInsulin resistanceDysregulation of adipokine secretion
06

Interacting drugs

Insulin

3 more in the full profile.

07

Biomarkers

Membrane phospholipid compositionHormone receptor densityGLUT4 expression

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