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Target intelligence / Profile preview
Adipose-derived mesenchymal stem cell
- Molecular classification
- Stem cell, Mesenchymal stem cell
01
Overview
Adipose-derived mesenchymal stem cells are multipotent adult progenitor cells from fat tissue capable of differentiating into various connective tissue lineages. Their ease of harvest and robust regenerative/paracrine properties make them highly valuable in research and clinical regenerative medicine settings.
- Other names
- ASCADMSCAdipose-derived stromal/stem cellAT-MSC
02
Mechanism of action
Paracrine signaling via cytokine and growth factor release; direct differentiation into damaged tissue types; immunomodulation.
03
Biological functions
Tissue repairImmunomodulationParacrine signalingDifferentiation (adipocytes, osteoblasts, chondrocytes, myocytes)
04
Disease associations
Soft-tissue injuriesBone/cartilage defectsSkin woundsCardiac/myocardial infarctionLiver diseaseNervous system disorders
05
Safety considerations
TumorigenicityImmune rejectionDelivery method complications
06
Biomarkers
CD73CD90CD105Absence of CD14Absence of CD11bAbsence of CD45Absence of CD19Absence of CD79a/bAbsence of HLA-DR
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