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ADP-ribosyltransferase 5 pseudogene (ENSG00000274664) is classified as a pseudogene related to the ADP-ribosyltransferase 5 (ART5) gene family. Pseudogenes are genomic DNA sequences similar to normal genes but non-functional: they have lost their protein-coding ability or are otherwise defective due to mutations such as insertions, deletions, or premature stop codons[5][8]. Pseudogenes are generally transcribed at low levels, if at all, and do not produce functional proteins. The ADP-ribosyltransferase family to which this pseudogene is related are enzymes involved in post-translational modification, but this pseudogene (ENSG00000274664) does not encode a functional enzyme[9]. Pseudogenes like this one may occasionally have regulatory roles at the RNA level, but such functions are not established for this specific locus.
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