Target intelligence / Profile preview

Air Leak Syndrome (ALS)

Target
ALS
Molecular classification
Other
01

Overview

An air leak occurs when air moves from a cavity where it is normally found into spaces where it is not, potentially causing respiratory distress and other complications. This can lead to conditions such as pneumothorax, where air enters the pleural space around the lungs, or pneumoperitoneum, where air enters the abdominal cavity.

Other names
Air Leak SyndromePneumothoraxPneumopericardiumPneumoperitoneum
02

Mechanism of action

Various treatments aim to resolve air leaks, such as chest tube drainage or surgery

03

Biological functions

Gas exchange compromiseblood flow compromiserespiratory distress
04

Disease associations

Respiratory distresstraumatic injurysurgical complications
05

Safety considerations

Potential for severe complications, including tension pneumothorax
06

Biomarkers

breathlessnessrapid heart ratechest pain

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