Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
AKAP13 antisense RNA 1 (AKAP13-AS1)
- Target
- AKAP13-AS1
- Molecular classification
- Long non-coding RNA (lncRNA)
01
Overview
AKAP13 antisense RNA 1 (AKAP13-AS1) is a long non-coding RNA gene discovered in the human genome, located on chromosome 15. It regulates gene expression potentially by modulating the expression or function of its sense counterpart AKAP13, which encodes a protein involved in key signaling pathways such as mTOR and GPCR signaling. AKAP13-AS1 itself does not encode a protein but may influence cellular cancer pathways, including acute myeloid leukemia progression, by acting as an upstream regulator in axes like ZNF667-AS1/miR-206/AKAP13. While AKAP13 is a recognized protein with signal transduction functionality and disease relevance, AKAP13-AS1 is not classified as a druggable target but may be relevant as a biomarker or in molecular diagnostic panels
- Other names
- AKAP13 antisense RNA 1AKAP13-AS1ENSG00000259367
02
Mechanism of action
Not applicable for drugs, as this molecule is a non-coding RNA and not a direct therapeutic target
03
Biological functions
Gene expression regulationPotential involvement in cancer as a regulatory RNA
04
Disease associations
Cancer (specifically implicated as a regulatory molecule influencing cancer signaling and prognosis via related axes, e.g., miR-206/AKAP13 in acute myeloid leukemia)Other (as a biomarker in cancers, based on regulatory involvement suggested in recent research)
05
Biomarkers
Potential biomarker for cancer prognosis (acute myeloid leukemia and possibly other cancers, mainly as part of molecular axes involving miR-206 and AKAP13)
Beyond the preview
Go deeper on AKAP13 antisense RNA 1 (AKAP13-AS1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on AKAP13 antisense RNA 1 (AKAP13-AS1).