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AKR7A2 pseudogene 1 (AKR7A2P1)

Target: AKR7A2P1
Molecular classification: Other (Pseudogene; not an enzyme, receptor, transporter, or other standard drug target class[3])

Overview

AKR7A2 pseudogene 1 (AKR7A2P1, AFARP1) is a processed pseudogene in the human genome related to the aldo-keto reductase family 7 member A2 gene (AKR7A2). Unlike its functional counterpart AKR7A2, which is involved in detoxification of aldehydes and the biosynthesis of gamma-hydroxybutyrate[1][2], AKR7A2P1 does not encode a functional protein product and is not considered a molecular target for therapeutic intervention[3].\nThe confusion may arise because its name is similar to AKR7A2 (a detoxifying enzyme with multiple biological and clinical roles), but as a *pseudogene* it does not share those functions or targetability[3]. If you are seeking information about an actual targetable protein or enzyme, search instead for “Aldo-keto reductase family 7 member A2 (AKR7A2)” rather than AKR7A2P1.

Other names: AFARP1Aldo-keto reductase family 7 A2 pseudogene 1

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