ALDH1L1 antisense RNA 1 (ALDH1L1-AS1)

ALDH1L1 antisense RNA 1 (ALDH1L1-AS1) is a long non-coding RNA (lncRNA), transcribed in the antisense direction relative to the coding gene ALDH1L1; it is also known as SLC41A3-AS1 and related synonyms[4][9]. This RNA molecule is not translated into protein but is thought to play regulatory roles in gene expression, including possible involvement in cell proliferation, apoptosis, and migration[9]. Currently, ALDH1L1-AS1 is not considered a direct therapeutic target, receptor, enzyme, transporter, or traditional drug target; instead, it is studied as a regulatory RNA with potential roles in biology and cancer. Functional associations and disease links remain under active investigation.\n\n**Notes on ambiguity:**\nALDH1L1 antisense RNA 1 should not be confused with the protein-coding gene ALDH1L1, which is an enzyme with known tumor suppressor activity and several disease associations. The protein-coding ALDH1L1 has well-characterized functions, while ALDH1L1-AS1 is a distinct, non-coding RNA[4][9].

Other names

SLC41A3-AS1ALDH1L1 and SLC41A3 antisense RNA 1ALDH1L1 antisense RNA 1 (non-protein coding)SLC41A3 antisense RNA 1ALDH1L1-AS1