Aldo-keto reductase family 1 member B1 pseudogene 6 (AKR1B1P6)

Aldo-keto reductase family 1 member B1 pseudogene 6 (AKR1B1P6) is a genomic pseudogene located in the human genome, related to the AKR1B1 gene, which encodes the enzyme aldose reductase[1][3][4][5][6]. Pseudogenes like AKR1B1P6 arise from duplication or retrotransposition events but typically lack the ability to code for a functional protein. There is currently no evidence that AKR1B1P6 encodes an active transcript or protein, nor is it implicated as a disease gene, therapeutic target, or biomarker. Its parental family, the aldo-keto reductases, are enzymes involved in various metabolic pathways, but AKR1B1P6 itself is classified as a non-functional pseudogene[3][4][5].

None (Pseudogenes are not drug targets and do not have mechanisms of action relevant for drug discovery.)