Aldo-keto reductase family 1 member C6, pseudogene (AKR1C6P)

Aldo-keto reductase family 1 member C6, pseudogene (AKR1C6P) is a human pseudogene belonging to the aldo-keto reductase superfamily, a large group of oxidoreductase enzymes that catalyze the reduction of aldehydes and ketones[1][4]. Unlike functional members of this family (e.g., AKR1C1, AKR1C3), AKR1C6P is non-coding and does not produce an active protein. As a pseudogene, it has no demonstrated enzymatic activity, known physiological function, established therapeutic relevance, or well-defined role in disease. Its name and sequence reflect homology to functional AKR enzymes, but it is considered genomically inert and not used as a drug target[3][5]. If you need information on a functional aldo-keto reductase family member for drug targeting or biological research, consider genes and proteins such as AKR1C1, AKR1C2, AKR1C3, etc., which are active enzymes involved in steroid metabolism, cancer, metabolic diseases, and are the focus of significant research and drug development[1][2][4].

Other names

TAKRtruncated aldo-keto reductase