ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase like 2 (ALG1L2)

ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase like 2 (ALG1L2) is a putative enzyme predicted to be involved in the process of protein glycosylation, specifically as a mannosyltransferase that may act within the endoplasmic reticulum[1][2][5][11]. The gene encodes a protein likely active in catalyzing the addition of mannose residues during N-glycan biosynthesis, similar to its paralog ALG1, but its precise biological activity remains unconfirmed and is based on sequence homology and predicted enzymatic function[1][2][9]. ALG1L2 currently has no confirmed role as a drug target and is not associated with any approved or investigational therapeutics, nor is it widely reported as a biomarker or associated with major pathologies outside of limited, putative disease associations such as proctitis[1][4].

Other names

Putative glycosyltransferase ALG1L2ALG1L2Asparagine-linked glycosylation 1-like 2