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Allergen-specific immunotherapy is a medical treatment aimed at strengthening the immune system to gradually reduce symptoms associated with allergies. It involves exposing patients to small, increasing amounts of allergens to build tolerance over time. This approach can lead to long-term relief from allergies by modifying the immune response through several mechanisms, including the induction of regulatory T cells (Treg) and the suppression of effector T cells and IgE production.
Modulation of T- and B-cell responses, suppression of IgE and activation of mast cells and basophils, induction of IgG4 and Treg cells.
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