Target intelligence / Profile preview

Aminopeptidase

Molecular classification: Enzyme, Exopeptidase, Metalloaminopeptidase, Cysteine aminopeptidase

Overview

Aminopeptidases are a class of exopeptidase enzymes that catalyze the cleavage of amino acids from the N-terminus of proteins or peptides. They are widely distributed and play essential roles in protein and peptide metabolism, including digestion and the regulation of bioactive peptides. Some aminopeptidases are implicated in diseases such as cancer, making them potential drug targets.

Mechanism of action

Hydrolyzes the terminal peptide bond at the N-terminal end of proteins and peptides, releasing single amino acid residues.

Biological functions

Protein metabolismPeptide metabolismDigestionRegulation of bioactive peptidesProtein turnover

Disease associations

CancerPain sensationBlood pressure regulationTumor progressionMetastasis

Interacting drugs

Bestatin

Beyond the preview

Go deeper on Aminopeptidase.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Aminopeptidase.

Explore the full profile