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Ammonium Ion (NH₄⁺)
- Target
- NH₄⁺
- Molecular classification
- Inorganic ion, Polyatomic ion
01
Overview
The ammonium ion (NH₄⁺) is a polyatomic cation formed by the protonation of ammonia. It plays a crucial role in nitrogen metabolism and acid-base balance in biological systems. While not a direct therapeutic target in the traditional sense, its levels are carefully monitored and managed in conditions like hepatic encephalopathy and urea cycle disorders. Treatments aim to reduce ammonia production or absorption.
- Other names
- Ammonium cationTetrahedral ammonium
02
Biological functions
Nitrogen metabolismAcid-base balance
03
Disease associations
Hepatic encephalopathy (related to ammonia levels)Urea cycle disorders (related to ammonia levels)
04
Safety considerations
Hyperammonemia (toxic levels of ammonia in the blood)Acidosis
05
Interacting drugs
Lactulose (reduces ammonia absorption)
1 more in the full profile.
06
Biomarkers
Plasma ammonia levels
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