Target intelligence / Profile preview

AMN1 antisense RNA 1 (AMN1-AS1)

Target: AMN1-AS1
Molecular classification: Long non-coding RNA (lncRNA), Antisense RNA, Non-coding RNA

Overview

AMN1 antisense RNA 1 (AMN1-AS1; AC023157.3) is a long non-coding antisense RNA transcribed from the opposite DNA strand at the AMN1 gene locus. Like other natural antisense transcripts (NATs), AMN1-AS1 is assumed to play a role in the regulation of gene expression at the AMN1 sense gene, likely through cis-acting mechanisms including transcriptional interference and/or modulation of RNA stability or chromatin structure. There is no evidence that AMN1-AS1 encodes a protein, acts as a receptor, enzyme, or typical therapeutic target class. There are currently no known drugs, clinical biomarkers, or established disease associations tied specifically to AMN1-AS1[3].

Other names: AC023157.3

Biological functions

Regulation of gene expression, likely through mechanisms common to antisense lncRNAs such as transcriptional interference, RNA stability modulation, chromatin modification, and possibly epigenetic regulation[1][2][6]

Disease associations

There is no direct evidence linking AMN1-AS1 to a major disease, but by analogy to other antisense lncRNAs, potential disease associations (such as in cancer or imprinting disorders) are possible but unconfirmed for this specific locus[4]

Beyond the preview

Go deeper on AMN1 antisense RNA 1 (AMN1-AS1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on AMN1 antisense RNA 1 (AMN1-AS1).

Explore the full profile