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Target intelligence / Profile preview
Amniotic Fluid Secretome (AFS)
- Target
- AFS
- Molecular classification
- Mixture, Growth Factors, Cytokines, Proteins, Extracellular Vesicles
01
Overview
The amniotic fluid secretome is the collection of bioactive molecules secreted by cells present in human amniotic fluid, primarily from fetal-origin cells. It comprises growth factors, cytokines, proteins, and extracellular vesicles, and its composition varies with gestational age. It plays critical roles in embryonic/fetal growth, neuroprotection, angiogenesis, immunomodulation, and tissue regeneration. The AFMSC-derived secretome has therapeutic potential in treating neurological injuries and inflammatory conditions.
- Other names
- Amniotic Fluid-derived FactorsAFMSC SecretomeAmniotic Fluid Conditioned Media
02
Mechanism of action
Multiple mechanisms of action including anti-apoptotic effects, axonal growth/neurogenesis promotion, and anti-inflammatory signaling.
03
Biological functions
Embryonic/Fetal Growth SupportNeuroprotectionAngiogenesisImmunomodulationTissue RegenerationCell-to-cell communication
04
Disease associations
Neurological InjuriesInflammationInflammatory Bowel Disease (IBD)
05
Safety considerations
Variability in composition based on gestational agePotential for immune responseNeed for standardized collection and processing methods
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