Target intelligence / Profile preview

Anaerobic bacterial metabolism

Molecular classification
Other (metabolic process)
01

Overview

Anaerobic bacterial metabolism refers to the processes by which bacteria generate energy in the absence of oxygen. This can involve anaerobic respiration, where inorganic or organic molecules serve as electron acceptors, or fermentation, where organic molecules are used to regenerate NAD+ from NADH. This metabolic flexibility allows bacteria to thrive in diverse environments and can influence their response to antibiotics and other stressors.

Other names
Anaerobic respirationanaerobic cellular respiration
02

Mechanism of action

Not applicable as a specific target but involves changes in gene expression and metabolic pathways in response to environmental conditions.

03

Biological functions

Energy productioncellular homeostasisadaptation to low oxygen environments
04

Disease associations

Infectionantibiotic resistance
05

Safety considerations

The shift to anaerobic metabolism can contribute to antibiotic resistance and persistence of infections
06

Interacting drugs

Antibiotics (e.g., ampicillin, tetracycline, gentamicin, co-trimoxazole) can influence anaerobic metabolism indirectly by inducing stress responses in bacteria

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