Anaphase-promoting complex subunit 16 (ANAPC16)

ANAPC16 (anaphase-promoting complex subunit 16) is a component of the anaphase-promoting complex/cyclosome (APC/C), a large multi-protein E3 ubiquitin ligase central to cell cycle control, particularly in the regulation of chromosome segregation and exit from mitosis[1][2]. The APC/C catalyzes ubiquitination of cell cycle proteins such as cyclins and securin, controlling their degradation and thus cell cycle progression[1][2]. While many APC/C subunits are well-characterized, ANAPC16 is relatively obscure and not individually cited in most reviews; its specific role remains unclear and no current evidence supports its status as a disease-related therapeutic target or biomarker[1][2][3]. Research interest is focused on the complex and its better-known subunits, not on ANAPC16 alone. If you require structured information relevant to the *APC/C* complex as a whole, or its main subunits, substantially more data is available. However, "anaphase-promoting complex subunit 16" is not a well-defined or actionable biomedical entity at present[1][2][3].

Other names

ANAPC16APC16

None reported for ANAPC16. Drug mechanisms targeting the APC/C involve inhibition of substrate recognition or E3 ligase function, but these target the overall complex or its key co-activators (not ANAPC16).