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Angiogenesis and Tissue Regeneration Pathways

Molecular classification
Other
01

Overview

The term "Angiogenesis and Tissue Regeneration Pathways" encompasses the coordinated set of molecular interactions and signaling events guiding the formation of new blood vessels (angiogenesis) and the subsequent growth or repair of tissues. These processes are vital for normal development, wound healing, and responses to tissue injury, but dysregulation plays a central role in diseases such as cancer (tumor angiogenesis), cardiovascular disorders, and chronic wounds. Canonical molecules involved include vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), platelet-derived growth factor (PDGF), angiopoietins, and their respective receptors, among others. Therapies targeting these components focus on either stimulating or inhibiting angiogenesis depending on the clinical context[1][2][3][4][5][6].

Other names
Angiogenesis pathwaysTissue regeneration pathwaysAngiogenic signalingAngiogenesis and repair signaling
02

Biological functions

Blood vessel formationTissue repairWound healingCell proliferationSignal transductionRegulation of microcirculation
03

Disease associations

CancerCardiovascular diseaseWound healing disordersIschemic diseaseOther

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