Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Angiogenesis Induction
- Molecular classification
- Biological Process, Cellular Process, Signaling Pathway
01
Overview
Angiogenesis induction is the physiological process involving the formation of new blood vessels from pre-existing vasculature. It is tightly regulated by a balance of pro-angiogenic and anti-angiogenic factors and plays critical roles in development, tissue repair, and disease. Aberrant angiogenesis is implicated in various pathologies, including cancer and ischemic diseases, making it an important therapeutic target.
- Other names
- NeovascularizationVascular growthBlood vessel formation
02
Mechanism of action
Modulation of pro-angiogenic and anti-angiogenic factors, including VEGF, FGF, Angiopoietins, Angiostatin, and Endostatin. Targeting signaling pathways such as PI3K/AKT and MAPK.
03
Biological functions
Embryonic developmentTissue growthWound healingReproductive functionsRegulation of blood flowExtracellular matrix remodelingCell migrationCell proliferationVascular permeability
04
Disease associations
CancerIschemic heart diseaseWound healingDiabetic retinopathyAge-related macular degenerationInflammationArthritis
05
Safety considerations
Excessive angiogenesis (e.g., tumor growth)Insufficient angiogenesis (e.g., impaired wound healing)Side effects of anti-angiogenic drugs (e.g., hypertension, proteinuria, bleeding)Resistance to anti-angiogenic therapies
06
Interacting drugs
Bevacizumab
2 more in the full profile.
07
Biomarkers
VEGF levelsAngiogenic factors in serum/tissueMicroRNA expression (angiomiRs)
Beyond the preview
Go deeper on Angiogenesis Induction.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Angiogenesis Induction.