Angiogenesis process (None)

The angiogenesis process refers to the physiological mechanism by which new blood vessels are formed from pre-existing vasculature. This tightly regulated biological event is crucial during embryonic development for organ formation but also occurs throughout life during tissue repair and regeneration. In adults it is largely dormant except when triggered by signals such as hypoxia or injury. Pathologically increased angiogenesis underlies tumor growth—enabling cancers to expand beyond their original size—and contributes to diseases like diabetic retinopathy and rheumatoid arthritis. Conversely insufficient angiogenesis impairs wound healing and recovery from ischemic events. Note: "Angiogenesis process" describes a complex multicellular event rather than a discrete molecular target; thus it does not fit standard drug target categories like "receptor," "enzyme," etc., making it an incorrect entry if seeking specific molecular targets. Angiogenesis is defined as the formation of new blood vessels from existing ones... It plays critical roles in both normal physiology—such as development and wound healing—and disease states including cancer progression.

Other names

AngiogenesisNeovascularizationBlood vessel formation

Drugs targeting the angiogenesis process generally act by inhibiting proangiogenic signaling pathways—most notably VEGF/VEGFR signaling—or by blocking other key mediators involved in endothelial cell proliferation and migration required for new blood vessel formation.