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Angiogenesis Stimulation
- Molecular classification
- Biological Process
01
Overview
Angiogenesis stimulation refers to the activation or enhancement of the physiological process by which new blood vessels form from pre-existing vasculature. This process is essential for normal growth, development, wound healing, and tissue regeneration. It is regulated by a complex interplay of pro-angiogenic factors (e.g., VEGF, FGFs, PDGF, Angiopoietins) and signaling pathways. Therapeutic stimulation of angiogenesis is being explored in ischemic diseases, while inhibition is targeted against tumor growth.
- Other names
- NeovascularizationVascular growthAngiogenesis
02
Biological functions
Blood vessel formationTissue repairEmbryonic developmentWound healing
03
Disease associations
Cancer (tumor angiogenesis)Diabetic retinopathyCardiovascular diseases (ischemic heart disease, peripheral artery disease)Wound healing disorders
04
Safety considerations
Uncontrolled angiogenesis in cancerPotential for off-target effects
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