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Target intelligence / Profile preview
ANKRD33B pseudogene 10 (ANKRD33BP10)
- Target
- ANKRD33BP10
- Molecular classification
- Pseudogene, Non-coding DNA
01
Overview
ANKRD33B pseudogene 10 (ANKRD33BP10) is a pseudogene located in the human genome, homologous to the ANKRD33B gene but rendered nonfunctional by various mutations or loss of regulatory elements[1][2][4][5]. Like other pseudogenes, it does not encode a functional protein, and there is no evidence it serves as a receptor, enzyme, or therapeutic target. Pseudogenes typically arise through gene duplication or retrotransposition, and while some may have gene regulatory or evolutionary roles, ANKRD33BP10 is currently annotated as nonfunctional with no known biological roles or disease associations. Not a therapeutic target; pseudogene status means it is nonfunctional, lacks drug interactions, mechanisms of action, or validated disease links. No practical use as a drug target, diagnostic, or biomarker under current scientific understanding[1][2][4][5][6].
- Other names
- ANKRD33B Pseudogene 10HGNC: 56302NCBI Gene: 100420022Ensembl: ENSG00000254916Previous GeneCards Identifiers (multiple legacy IDs)
02
Mechanism of action
None. As a pseudogene, it does not serve as a druggable entity.
03
Biological functions
None, direct. Pseudogenes lack protein-coding function. Some pseudogenes may have regulatory effects (e.g., acting as microRNA decoys, sources for long non-coding RNAs, or gene expression regulators) in other contexts, but no such functions are documented for ANKRD33BP10 specifically.
04
Disease associations
None known for ANKRD33BP10. Although some pseudogenes can influence disease states, including acting as miRNA decoys or regulators in cancer (e.g., PTENP1, BRAFP1), there is no evidence for a disease association for ANKRD33BP10.
05
Safety considerations
None. No safety concerns are documented; pseudogenes generally present interpretative challenges in molecular diagnostics, since their similarity to protein-coding genes can complicate genetic testing and sequencing.
06
Interacting drugs
None known
07
Biomarkers
None known
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