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Ankyrin repeat domain 11 pseudogene
- Molecular classification
- Pseudogene
01
Overview
Ankyrin repeat domain 11 pseudogene is a non-functional copy of the protein-coding ankyrin repeat domain 11 gene. Like other pseudogenes, it shares high sequence similarity with its parent gene but has accumulated mutations (such as frameshifts or stop codons) that prevent it from encoding a functional protein. Pseudogenes such as this are broadly considered nonfunctional "genomic fossils," though in rare cases they may produce RNA transcripts with potential regulatory effects. However, current evidence does not support any clear biological, pathological, or pharmacological role for the ankyrin repeat domain 11 pseudogene.
- Other names
- ANKRD11P
02
Mechanism of action
Not applicable
03
Biological functions
Possible weak influence on gene regulation via non-coding RNA mechanisms (e.g., regulation of the parental ANKRD11 gene via RNA interference in rare circumstances, but lacks direct biological function)
04
Disease associations
None directly. Functional ANKRD11 mutations are associated with KBG syndrome, but the pseudogene itself does not have a known disease association
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