Target intelligence / Profile preview

Ankyrin repeat domain-containing protein 13C (ANKRD13C)

Target
ANKRD13C
Molecular classification
Other (Ankyrin repeat domain-containing protein), Molecular chaperone for G protein-coupled receptors[9][11][12]
01

Overview

Ankyrin repeat domain-containing protein 13C (ANKRD13C) is a human protein encoded by the ANKRD13C gene. It functions primarily as a molecular chaperone for G protein-coupled receptors (GPCRs), regulating their proper folding, biogenesis, and facilitating their exit from the endoplasmic reticulum to ensure trafficking to the appropriate cellular compartments[9][10][11][12]. ANKRD13C contains ankyrin repeat domains, which are known for mediating protein-protein interactions. No direct therapeutic drugs, established biomarker roles, or identified clinical safety concerns are currently associated with this protein[9][10][11][12]. The gene and protein are not recognized as established therapeutic targets such as receptors, enzymes, or drug transporters, and current evidence links them to general protein folding and trafficking processes rather than specific disease phenotypes.

Other names
ANKRD13Cankyrin repeat domain 13CdJ677H15.3DKFZP566D1346
02

Biological functions

Regulation of G protein-coupled receptor (GPCR) biogenesis[9][10][11][12]Regulation of GPCR exit from the endoplasmic reticulum (ER)[9][10][11][12]Signaling receptor binding[1][3]
03

Disease associations

Other (no established direct role in specific diseases reported)

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