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Target intelligence / Profile preview
Ankyrin repeat domain-containing protein 30A (ANKRD30A)
- Target
- ANKRD30A
- Molecular classification
- Transcription factor, DNA-binding protein
01
Overview
ANKRD30A is a tissue-specific transcription factor that serves as a differentiation antigen of the mammary gland, with potential applications in breast cancer immunotherapy due to its restricted expression pattern and association with favorable prognosis.
- Other names
- NY-BR-1Breast cancer antigen NY-BR-1Serologically defined breast cancer antigen NY-BR-1
02
Mechanism of action
Immunotherapy target, Tumor antigen recognition
03
Biological functions
Transcription regulationCell differentiationMammary gland development
04
Disease associations
CancerBreast cancer
05
Safety considerations
Limited to specific patient populations based on HLA class I co-expression
06
Interacting drugs
Investigational immunotherapeutic agents
1 more in the full profile.
07
Biomarkers
Breast cancer prognosisTumor grade assessmentImmunotherapy patient selection
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