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Ankyrin repeat domain-containing protein 30B (ANKRD30B)
- Target
- ANKRD30B
- Molecular classification
- Other (Protein containing ankyrin repeats; not a receptor, ion channel, enzyme, transporter, or transcription factor[5][6].), Ankyrin repeat-containing protein
01
Overview
Ankyrin repeat domain-containing protein 30B (ANKRD30B) is a protein encoded by the human *ANKRD30B* gene. The protein contains ankyrin repeat domains that typically mediate protein-protein interactions critical for cellular function in various protein families[5][6]. While the exact biological function of ANKRD30B is not clearly established, its expression has been associated with breast cancer (as serologically defined antigen NY-BR-1.1) and spastic ataxia 4[2]. ANKRD30B does not belong to classical molecular families such as receptors, enzymes, or transcription factors—rather, it is classified as an ankyrin repeat-containing protein. No approved drugs are known to interact with ANKRD30B, nor is it a recognized therapeutic target. Its potential utility as a biomarker in breast cancer and related research is noted[2][5].
- Other names
- Ankyrin repeat domain-containing protein 30BANKRD30BNY-BR-1.1Serologically defined breast cancer antigen NY-BR-1.1
02
Biological functions
Proposed involvement in protein-protein interactions (due to ankyrin repeat structure)[6]Limited direct functional characterization; biological role remains uncertain[5]
03
Disease associations
Cancer (specifically breast cancer; identified as a serological antigen and biomarker)[2]Neurodegenerative disease (spastic ataxia 4[2])
04
Biomarkers
May act as a biomarker for breast cancer (as a serologically defined antigen)[2]
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