Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Ankyrin repeat domain-containing protein 42 (ANKRD42)
- Target
- ANKRD42
- Molecular classification
- Other (Ankyrin repeat domain-containing protein), Protein phosphatase 1 regulatory subunit (PPP1R family)
01
Overview
Ankyrin repeat domain-containing protein 42 (ANKRD42) is a protein encoded by the ANKRD42 gene in humans. It belongs to the protein phosphatase 1 regulatory subunit (PPP1R) and ankyrin repeat domain-containing (ANKRD) protein families. ANKRD42 is predicted to play a role in modulating cellular signaling pathways, including the positive regulation of NF-kappaB transcription factor activity and cytokine production involved in inflammatory response. It may act as an inhibitor of cyclin-dependent protein serine/threonine kinases and has been linked to tissue remodeling pathways. Although it demonstrates widespread expression across tissues and participates in multiple cellular processes, current evidence does not indicate a direct role as a drug target or established disease biomarker[1][2][10][9].
- Other names
- SARPPPP1R79Several ankyrin repeat proteinFLJ37874Protein phosphatase 1, regulatory subunit 79Ankyrin repeat domain 42ANR42_HUMAN (UniProt entry name)
02
Biological functions
Positive regulation of NF-kappaB transcription factor activityCyclin-dependent protein serine/threonine kinase inhibitor activityPositive regulation of cytokine production involved in inflammatory responsePotential modulation of tissue remodeling and cellular signaling pathways, especially via YAP1-dependent mechanisms
03
Disease associations
Other
Beyond the preview
Go deeper on Ankyrin repeat domain-containing protein 42 (ANKRD42).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Ankyrin repeat domain-containing protein 42 (ANKRD42).