Target intelligence / Profile preview

Ankyrin repeat domain-containing protein 66 (ANKRD66)

Target
ANKRD66
Molecular classification
Other (Ankyrin repeat-containing protein; not an enzyme, receptor, transporter, ion channel, transcription factor, or histone modifier)
01

Overview

ANKRD66 is a protein that contains ankyrin repeat domains, modular protein motifs that typically mediate protein-protein interactions. The ANKRD66 gene is protein-coding and mapped to human chromosome 6. It is listed as associated with Dandy-Walker syndrome in genetic databases, but its specific biological role, molecular mechanisms, and relevance as a therapeutic target have not been characterized. No known drugs or interventions directly target this protein, and it features structurally as an ankyrin repeat-containing protein rather than belonging to a major drug target family such as receptors, enzymes, or ion channels. If you need structured information for database or analytical purposes, the current scientific consensus is that ANKRD66 remains poorly characterized and is not presently considered a therapeutic target. Most available data relates to gene sequence and protein structure classification, not pharmacological or pathophysiological significance.

Other names
ANKRD66ankyrin repeat domain 66ankyrin repeat domain-containing protein 66
02

Disease associations

Dandy-Walker syndrome (gene associated with this developmental syndrome, though the mechanism and significance are unclear and not established as causative)

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