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Target intelligence / Profile preview
ANO1 antisense RNA 1 (ANO1-AS1)
- Target
- ANO1-AS1
- Molecular classification
- Long non-coding RNA, lncRNA
01
Overview
ANO1 antisense RNA 1 (ANO1-AS1) is a long non-coding RNA transcribed from the genomic region complementary to the ANO1 gene (also known as TMEM16A). ANO1-AS1 is believed to play a role in the regulation of ANO1 expression at the transcriptional or post-transcriptional level, potentially through mechanisms common to other antisense lncRNAs, such as modulation of mRNA stability, splicing, or epigenetic regulation. While it may contribute to the regulation of cancer-related processes by controlling ANO1 levels, ANO1-AS1 is not itself a therapeutic target, receptor, or enzyme, and there are no approved drugs directly acting on this lncRNA. Most therapeutic research in this area focuses on ANO1 rather than its antisense transcript.
- Other names
- ANO1-AS1ANO1 antisense RNA 1lncRNA ANO1-AS1long non-coding RNA ANO1-AS1
02
Biological functions
Regulation of gene expression (particularly of ANO1)Epigenetic regulationRoles in cancer cell proliferation or metastasis control by regulating ANO1
03
Disease associations
CancerEpigenetic disease
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