Anti-inflammatory activity via natural compounds

Anti-inflammatory activity via natural compounds refers to the ability of naturally occurring molecules to modulate or suppress inflammatory processes. These compounds act on various molecular targets and signaling pathways involved in inflammation, including NFκB, MAPK, COX, LOX, and proinflammatory cytokines. They offer potential alternatives or adjuncts to conventional anti-inflammatory drugs, particularly for chronic conditions and general health maintenance. Key compounds include polyphenols like curcumin, resveratrol and quercetin, as well as omega-3 fatty acids and gingerol. They generally have a favorable safety profile compared to synthetic drugs but may not match the potency required for severe acute inflammation.

Other names

Natural anti-inflammatory compoundsPlant-derived anti-inflammatoriesDietary anti-inflammatory agents

Inhibition of signaling cascades, downregulation of cytokine secretion, blockade of enzyme activities, reduction in eicosanoid synthesis, antioxidant effects, immunomodulatory actions, analgesic effects.