Anti-inflammatory and Antioxidant Activity (None)

Anti-inflammatory and antioxidant activity refers to the biological processes or molecular mechanisms that reduce inflammation and oxidative stress in cells or tissues. These activities are not attributed to a single molecule or receptor but rather encompass a range of pathways, enzymes, transcription factors, and small molecules that collectively modulate immune responses and protect against cellular damage caused by reactive oxygen species (ROS) and pro-inflammatory mediators. Key targets include NF-κB, MAPK, COX-II, iNOS, and proinflammatory cytokines.

Other names

Anti-inflammatory activityAntioxidant activity

Inhibition of NF-κB, AP-1, and NF-AT transcription factors; suppression of MAPK/JNK/Akt/IκK/NF-κB signaling pathways; scavenging of reactive oxygen species (ROS); inhibition of COX-II and iNOS; reduction of proinflammatory cytokine production (TNF-alpha, IL-1β, IL-6)