Anti-inflammatory and immunomodulatory

"Anti-inflammatory and immunomodulatory" refers to a broad category of therapeutic approaches rather than a specific molecular target. These therapies aim to modify immune system function to treat various conditions including autoimmune diseases, inflammatory disorders, cancer, and neurodegenerative diseases. Immunomodulators can either enhance (immunostimulants) or suppress (immunosuppressants) immune responses. They target various molecular pathways including cytokine signaling, leukocyte activation, and cell adhesion. Specific molecular targets within this category include proinflammatory cytokines, their receptors, adhesion molecules, and various signaling pathways like NF-κB. Drug classes include biologics (such as monoclonal antibodies), small molecules, peptides, and natural products.

Other names

Immunomodulatory agentsAnti-inflammatory drugsImmunosuppressantsImmunostimulants

Inhibition of cytokine signaling, Decreasing leukocyte activation, Reducing chemotaxis and recruitment, Targeting proinflammatory cytokines and their receptors, Modulating adhesion molecules