Anti-inflammatory effect via multi-herbal constituents

"Anti-inflammatory effect via multi-herbal constituents" describes the aggregate capacity of diverse herbal compounds—such as curcumin (turmeric), glycyrrhizin (licorice), rosmarinic acid (rosemary), and others—to modulate inflammatory processes through a variety of mechanisms. These herbs often target multiple molecular pathways involved in the initiation and propagation of inflammation, including suppression of proinflammatory cytokines (TNF-α, IL-6, IL-1β), inhibition of key signaling molecules (NF-κB, MAPKs), and blocking enzymes (COX, LOX). Because these effects are the result of polypharmacology—many compounds acting on many targets in concert—the term does not specify a discrete molecular entity or drug target[1][2][3][4].

Modulation of multiple pro-inflammatory signaling pathways (including inhibition of NF-κB, MAPK, COX, LOX, inflammatory cytokines such as TNF-α, IL-1β, IL-6; altering complement system; reduction of leukocyte-endothelial adhesion)[1][2][3][4]