Antioxidant activity via free radical scavenging (N/A)

Antioxidant activity via free radical scavenging refers to the ability of molecules (antioxidants) to neutralize free radicals, preventing cellular damage caused by oxidative stress. This mechanism is vital for protecting biological systems from degenerative diseases linked to oxidative damage. Antioxidants achieve this by donating electrons or hydrogen atoms to free radicals, converting them into stable, less reactive species. Key mechanisms include Hydrogen Atom Transfer (HAT), Single Electron Transfer followed by Proton Transfer (SET-PT), and Sequential Proton Loss Electron Transfer (SPLET). Molecules involved include phenolic compounds, vitamins, and antioxidant enzymes. Assessment of antioxidant activity is performed using assays like DPPH, ABTS, and ORAC. Maintaining sufficient antioxidant capacity is important for preventing and treating diseases associated with chronic oxidative stress.

Other names

Free radical scavenging activityAntioxidant defenseROS scavengingRNS scavenging

Hydrogen Atom Transfer (HAT), Single Electron Transfer followed by Proton Transfer (SET-PT), Sequential Proton Loss Electron Transfer (SPLET)